Keep reading to learn more about the possible benefits of butyric acid and what researchers have unearthed about it so far.
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Early evidence looks promising, though. Researchers are continuing to look at the potential that butyric acid has for improving gut health.
To date, only limited research has been done, especially on humans, to fully understand the benefits of butyric acid.
It&#;s also found in animal fats and vegetable oils. However, the amount of butyric acid found in foods like butter and ghee is small compared to the amount that&#;s made in your gut.
Butyric acid is a fatty acid that&#;s created when the good bacteria in your gut break down dietary fiber .
Butyric acid goes by several other names, including butyrate and butanoic acid.
The primary health benefits of butyric acid and other SCFAs are their ability to provide your colon cells with energy. Butyric acid provides your colon cells with about 70 percent of their total energy needs.
SCFAs are saturated fatty acids that are created when friendly bacteria break down dietary fiber.
These three fatty acids make up between 90 and 95 percent of the SCFAs in your gut.
Butyric acid is what&#;s known as a short-chain fatty acid (SCFA) . It&#;s one of the three most common SCFAs in your gut, along with acetic acid and propionic acid.
You&#;ve likely heard that eating fiber is good for your digestion. Part of the reason why eating more fiber may improve your gut health is because it leads to your colon producing more butyric acid.
Although clinical evidence is limited, early research suggests butyric acid could have several benefits, as outlined below.
Some research suggests taking butyric acid supplements could potentially be used as a treatment for irritable bowel syndrome (IBS) and Crohn&#;s disease.
In one double-blind, randomized placebo study, 66 adults with IBS received a daily dose of either 300 milligrams (mg) of sodium butyrate or a placebo. After 4 weeks, participants in the butyric acid group reported significantly less abdominal pain.
In another study, researchers gave 13 patients with Crohn&#;s disease 4 grams of butyric acid a day for 8 weeks. At the end of the 8-week treatment, 9 of the 13 participants had improved symptoms.
Most of the research looking at butyric acid&#;s ability to prevent or treat colon cancer has been done on animals or isolated cells.
In one study, researchers found that sodium butyrate blocked the growth of colorectal cancer cells. The same study also found it increased the rate of cell death.
Researchers suggest a higher intake of dietary fiber, which could increase the amount of butyric acid the gut produces, may help reduce the risk of colon cancer.
However, more human studies are needed to explore this.
People with type 2 diabetes often have low amounts of butyric acid&#;producing bacteria in their gut.
Animal studies have shown that increasing dietary fiber intake may improve insulin sensitivity and lower the risk of obesity.
However, at this point in time, there&#;s limited evidence to suggest increasing butyric acid in humans has the same effect on insulin sensitivity.
Butyric acid is a vital fatty acid produced when the good bacteria in the gut break down dietary fibre. It is naturally found in animal fats and vegetable oils, however, the quantity of butyric acid found in food sources is less compared to the amount produced in the gut.
Butyric acid is known as a short-chain fatty acid (SCFA), which is one among the three most common SCFA&#;s in the gut, along with acetic acid and propionic acid. These saturated fatty acids comprise about 90-95 % of the SCFAs in the gut that is produced when gut-friendly bacteria break down dietary fibre. Butyric acid is well-known to support digestive health, reduce inflammation and lowers the risk of diseases and promote overall health. It holds a significant role in providing colon cells with the needed energy to carry out its normal functions and also regulates blood sugar and cholesterol levels. It goes by other names such as butyrate and butanoic acid.
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Butyric acid serves as a chief source of energy for colon cells, which make up the lining of the intestine. While most of the body cells utilise glucose as the main source of energy, the colon cells lining gut chiefly use butyrate, without butyrate these cells are unable to perform normal functions. The short-chain fatty acids offer an oxygen-free environment that supports the growth of gut microbes that controls inflammation and maintain gut cells healthy.
Also Read: Prebiotics: 5 Awesome Foods That Uphold Gut Health-Infographic
Butyrate guards the cells against detrimental substances to keep gut healthy and disease-free. A colon is a storage place of the waster products. Higher levels of butyrate have shown to increase levels of glutathione, an antioxidants made in the system which neutralises free radicals in the gut. This improves the barrier function of the colonocytes and lowers the risk of bowel cancer, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS).
Regular intake of high fibre diet increases the amount of butyric acid produced in the gut which is well-known to reduce the risk of colon cancer. Studies have proven that butyric acid is a potential to prevent and treat colon cancer by blocking the growth of colorectal tumour cells. Moreover, it also leads to apoptosis that stops the growth of cancer cells completely.
Studies show that butyrate stimulates the secretion of gut hormones such as glucagon &#;like-peptide -1(GLP-1) and peptide YY (PYY).GLP-1 hormones increase insulin secretion and lower the production of glucagon in the pancreas. While the PYY hormones promote the uptake of glucose in muscles and fatty tissue. Thus the presence of butyric acid increases the secretion of gut hormones that regulate type 2 diabetes and control weight
Butyric acid plays a key role in promoting neuroprotective effects that trigger brain and nervous system function. Butyrate targets several pathways linked with the progression of neurodegenerative diseases like Parkinson&#;s, Alzheimer&#;s stroke and autism. A diet abundant in butyric acid is an effective way to improve disease outcomes and uplift overall health.
Generally, most of the butyric acid in the body is made from the gut bacteria. While some amount of butyric acid is also found naturally in food sources which include:
Ghee
Cow&#;s milk
Butter
Sheep&#;s milk
Breast milk
Parmesan cheese
Red meat
Vegetable oils
Sauerkraut
Butter is one of the richest sources of butyric acid. It is also available in the form of dietary supplement as sodium butyrate. However, increasing the intake of dietary fibre can also help to boost butyric acid level in the gut. The gut bacteria chiefly feed on resistant starches which the body can&#;t break down. Some of the good sources of resistant starches, pectin found in many fruits and inulin.
Also Read: Dietary Fibre And Its Role In Preventing Chronic Diseases
Garlic
Onions
Asparagus
Potatoes
Bananas
Apples
Apricots
Carrots
Oat bran
Butyric acid is one of the most beneficial short-chain fatty acids that play a key role in uplifting digestive health, reduces inflammation, protects the brain, manages weight and prevent cancer. The gut bacteria in the body make butyrate from the foods you can&#;t digest, which renders the body with a host of health benefits. Enriching your diet with fibre will help to elevate the butyric acid production by the gut flora.
The content provided here is for informational purposes only. This blog is not intended to substitute for medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider for any questions or concerns you may have regarding a medical condition. Reliance does not endorse or recommend any specific tests, physicians, procedures, opinions, or other information mentioned on the blog.
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