Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

12 Mar.,2024

According to the data searched by the Magic Mirror market, in the Tmall and Taobao markets, ginseng medicine and food have the same ingredients, and have a growth rate of 59.68%, rapidly occupying the market.

 

According to the data searched by the Magic Mirror market, in the Tmall and Taobao markets, ginseng medicine and food have the same ingredients, and have a growth rate of 59.68%, rapidly occupying the market.

 

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

 

It is not surprising that ginseng is popular in the market. Tracing back to the Chinese nourishing culture for thousands of years, according to the earliest pharmacopoeial "Shennong Materia Medica" records, ginseng has "tonifying the five viscera, calming the spirit, calming the soul, stopping panic palpitations, eliminating evil spirits, bright eyes, happy education, long take light body and prolong life", ginseng is known as "the king of hundred herbs", which occupies a pivotal position in the theory of traditional Chinese medicine. In recent years, with the progress of science and technology, ginsenosides, especially rare ginsenosides, which are active ingredients in ginseng, have been widely concerned by researchers and consumers. Rare ginsenosides, with their unique pharmacological effects and significant health benefits, are gradually becoming a new favorite for people to pursue a healthy life.

 

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

 

Ginsenosides, one of the main active components of ginseng, have many pharmacological effects. Ginsenosides are the main active substances of ginseng, which belong to three kinds of glycosides. They are condensed by sugar and aglycones, which have anti-tumor effect and the effect of lowering blood sugar and blood lipid. A large number of studies have proved that the rare ginsenosides with two or one glucoside bond produced by the desaccharification of intestinal bacteria have stronger biological activity. However, the content of rare ginsenosides in nature is extremely low, and relevant experimental data show that 10 kilograms of higher ginseng (red ginseng, long white ginseng, panax ginseng) can extract about 100mg of rare ginsenosides, accounting for only 0.001%. The price of rare ginsenosides in the international market is up to 360,000 RMB/gram, which is more scarce than gold.

The rare ginsenosides have stronger biological activity, which is conducive to maximize pharmacological effects. Ginsenosides can only be absorbed by the human body after entering the human body through specific enzyme decomposition, and this enzyme is rarely or not present in the human body, resulting in low bio-availability and weak pharmacological effects of ginsenoside tablets in the human body. The secondary metabolites of ginsenosides transformed by synthetic biology techniques (such as enzymatic hydrolysis or microbial fermentation) have stronger biological activity, and these secondary metabolites (F1, F2, Rg3, Rh1, Rh2, Rh3, CY, CM and CK) are called rare ginsenosides. Rare ginsenosides have better biological activity, and are more conducive to body absorption. They have sedative and hypnotic effects, promote cell differentiation and proliferation, anti-tumor, hypoglycemic, and enhance immunity, and can be used in skin care products, medical dressings, biomedical materials and health food.

 

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

Biosynthetic Pathways of Rare Ginsenosides 

 

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

According to research, the pharmacological activity of rare ginsenosides is mainly manifested in anti-fatigue, anti-aging, enhance immunity, protect cardiovascular and cerebrovascular system and anti-tumor, etc., and it has higher application value in modern medicine, health care and skin care. However, the content of rare ginsenosides in nature is very low, and it is difficult to extract them directly from plants. The research team found that the new biological transformation method of rare ginsenosides can transform the prototype ginsenosides into rare ginsenosides. Compared with the original ginsenosides, rare ginsenosides have the characteristics of more stable molecular structure, smaller molecular weight, higher fat solubility and clearer targeting, which greatly improve the bioavailability of ginseng. 

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food

 

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd. relies on the enzyme catalysis research team of Shaanxi Province Natural Active Products Industrialization Engineering Technology Research Center to provide a full range of cost-effective ginseng constants and rare ginsenosides.

 

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Cuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng FoodCuikang Pharmaceutical | Focuses on the New Exploration of Rare Ginsenosides, and is Committed to the Modern Solution of Ginseng Food