What is the Advantage and Disadvantage of CDP Choline

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Campos, E. C., Schiavi, C., Benedetti, P., Bolzani, R., and Porciatti, V. Effect of citicoline on visual acuity in amblyopia: preliminary results. Graefes.Arch Clin.Exp.Ophthalmol. ;233(5):307-312. View abstract.

Capurso A, Capurso S, Panza F, and et al. Efficacy of cytidine diphosphate choline in patients affected by chronic cerebrovascular disease. Clinical Drug Investigation ;12(1):26-38.

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Clark, W. M., Wechsler, L. R., Sabounjian, L. A., and Schwiderski, U. E. A phase III randomized efficacy trial of mg citicoline in acute ischemic stroke patients. Neurology. 11-13-;57(9):-. View abstract.

Clark, W. M., Williams, B. J., Selzer, K. A., Zweifler, R. M., Sabounjian, L. A., and Gammans, R. E. A randomized efficacy trial of citicoline in patients with acute ischemic stroke. Stroke. ;30(12):-. View abstract.

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D'Orlando, K. J. and Sandage, B. W., Jr. Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury. Neurol.Res ;17(4):281-284. View abstract.

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Fioravanti, M. and Yanagi, M. Cytidinediphosphocholine (CDP choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database.Syst.Rev. ;(2):CD. View abstract.

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Iranmanesh, F. and Vakilian, A. Efficiency of citicoline in increasing muscular strength of patients with nontraumatic cerebral hemorrhage: a double-blind randomized clinical trial. J Stroke.Cerebrovasc.Dis. ;17(3):153-155. View abstract.

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Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. ;33(4):e. View abstract.

Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res ;143:215-221. View abstract.

Licata SC, Penetar DM, Ravichandran C, et al. Effects of daily treatment with citicoline: a double-blind, placebo-controlled study in cocaine-dependent volunteers. J Addict Med ;5(1):57-64. View abstract.

Loebis R, Zulkarnain BS, Siswanto FA. Effectiveness of citicoline in pediatric patients with refractive amblyopia in Surabaya, East Java, Indonesia. J Basic Clin Physiol Pharmacol ;32(4):657-661. View abstract.

Marino PF, Rossi GCM, Campagna G, et al. Effects of citicoline, homotaurine, and vitamin E on contrast sensitivity and visual-related quality of life in patients with primary open-angle glaucoma: A preliminary study. Molecules. Nov 29;25(23):. View abstract.

Martí-Carvajal AJ, Valli C, Martí-Amarista CE, et al. Citicoline for treating people with acute ischemic stroke. Cochrane Database Syst Rev. Aug 29;8:CD. View abstract.

Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr ;151(8):-. View abstract.

Ottobelli L, Manni GL, Centofanti M, et al. Citicoline oral solution in glaucoma: is there a role in slowing disease progression? Ophthalmologica ;229(4):219-26. View abstract.

Parisi V, Centofanti M, Ziccardi L, et al. Treatment with citicoline eye drops enhances retinal function and neural conduction along the visual pathways in open angle glaucoma. Graefes Arch Clin Exp Ophthalmol ;253(8):-40. View abstract.

Parravano M, Scarinci F, Parisi V, et al. Citicoline and vitamin B12 eye drops in type 1 diabetes: Results of a 3-year pilot study evaluating morpho-functional retinal changes. Adv Ther. Apr;37(4):-. View abstract.

Pawar PV, Mumbare SS, Patil MS, Ramakrishnan S. Effectiveness of the addition of citicoline to patching in the treatment of amblyopia around visual maturity: a randomized controlled trial. Indian J Ophthalmol ;62(2):124-9. View abstract.

Rejdak R, Toczolowski J, Krukowski J, et al. Oral citicoline treatment improves visual pathway function in glaucoma. Med Sci Monit ;9:PI24-8. View abstract.

Roohi-Azizi M, Arabzadeh S, Amidfar M, et al. Citicoline combination therapy for major depressive disorder: a randomized, double-blind, placebo-controlled trial. Clin Neuropharmacol ;40(1):1-5. View abstract.

Rossetti L, Iester M, Tranchina L, et al. Can treatment with citicoline eyedrops reduce progression in glaucoma? The results of a randomized placebo-controlled clinical trial. J Glaucoma. Jul;29(7):513-520. View abstract.

Salamah A, Mehrez M, Faheem A, El Amrousy D. Efficacy of Citicoline as a Neuroprotector in children with post cardiac arrest: a randomized controlled clinical trial. Eur J Pediatr. Apr;180(4):-. View abstract.

Savci V, Goktalay G, Cansev M, et al. Intravenously injected citicoline increases blood pressure and reverses hypotension in haemorrhagic shock: effect is mediated by central cholinergic activation. Eur J Pharmacol ;468:129-39. View abstract.

Secades JJ, Alvarez-Sabín J, Castillo J, et al. Citicoline for acute ischemic stroke: a systematic review and formal meta-analysis of randomized, double-blind, and placebo-controlled trials. J Stroke Cerebrovasc Dis ;25(8):-96. View abstract.

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Sobrado M, Lopez MG, Carceller F, et al. Combined nipodimine and citicoline reduce infarct size, attenuate apoptosis, and increase BCL-2 expression after focal cerebral ischemia. Neuroscience ;118:107-13. View abstract.

Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol ;53:441-8. View abstract.

Teather LA, Wurtman RJ. Dietary cytidine (5)-diphosphocholine supplementation protects against development of memory deficits in aging rats. Prog Neuropsychopharmacol Biol Psychiatry ;27:711'17. View abstract.

Trimmel H, Majdan M, Wodak A, Herzer G, Csomor D, Brazinova A. Citicoline in severe traumatic brain injury: indications for improved outcome: a retrospective matched pair analysis from 14 Austrian trauma centers. Wien Klin Wochenschr. ;130(1-2):37-44. View abstract.

Weiss GB. Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline. Life Sci ;56:637-60. View abstract.

Zemel MB, Thompson W, Milstead A, et al. Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res ;12:582'90. View abstract.

Zweifler RM. Membrane stabilizer: Citicoline. Curr Med Res Opin ;18:s14-s17. View abstract.

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