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Check social media, and you&#;ll find thousands of glowing posts for the latest microbiome buzzword: #butyrate.
From TikTok to Instagram to Twitter, users and advertisers are posting shoutouts to this short-chain fatty acid, claiming it aids in everything from digestion to depression. Butyrate enthusiasts are adding fiber-rich sauerkraut to soup, bingeing on butter and kombucha, and taking supplements to boost levels in their bodies.
But what is butyrate, and can it really do all that its fans say it does? Or is it all hype and no help?
Early evidence, mostly from animal studies, suggests the truth may lie somewhere in between. Registered dietitian and gut microbiome researcher Gail Cresci, PhD, RD, explains what you need to know about butyrate.
Butyrate is produced when &#;good&#; bacteria in your gut help your body break down dietary fiber in your large intestine (colon). It&#;s one of several short-chain fatty acids, which are named for their chemical structure.
Dr. Cresci has studied butyrate for more than a decade. &#;It&#;s amazing how many beneficial things it does for the body,&#; she says.
Butyrate (pronounced &#;byoo-ter-ate&#;) plays an important role in digestive system health by providing the main energy source for your colon cells; it meets about 70% of their energy needs. And it may provide other health benefits, too, including supporting your immune system, reducing inflammation and preventing diseases like cancer.
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One type of butyrate is butyric (or butanoic) acid, a chemically modified version of butyrate sometimes used in foods and supplements.
Other types include:
Butter is a good source of butyrate, but you&#;d need to eat far more of it than is recommended; it&#;s high in saturated fat and can raise your risk of cardiovascular disease. Instead, boost your body&#;s butyrate levels by increasing your daily fiber intake with plant-based foods.
Because your body doesn&#;t break down fiber during the digestion process, it&#;s left for your gut bacteria to break down. Your healthy gut bacteria produce butyrate from dietary soluble, fermentable fibers that only they can break down.
Other sources include prebiotics and supplements that are high in fiber.
You can promote butyrate production by consuming foods high in fermentable fiber. For excellent natural sources, eat a healthy diet rich in:
Let&#;s break down some of those categories a little bit further.
Many fruits contain fermentable fibers, including:
Vegetables and legumes high in fiber include:
It&#;s wise to consume these foods in moderation (no more than 5% to 6% of your total daily calories) because they&#;re high in saturated fat and cholesterol. They include:
If you don&#;t consume much fiber, add it slowly to your diet and drink plenty of liquids to maintain hydration. You may experience some gas or bloating, but it&#;ll begin to subside in a couple of days, says Dr. Cresci.
&#;If you eat a lot of fiber and don&#;t drink a lot of water, you can get really constipated,&#; she says. &#;Also, look at your urine. Aim for a light yellow throughout the day, which means you&#;re adequately hydrated.&#;
Some supplements may encourage butyrate production, but you should talk to your healthcare provider before taking any. Most supplements use butyric acid and some kind of salt, but they haven&#;t been proven to be beneficial.
&#;The best way to get butyrate is to eat fresh fruits and vegetables that contain soluble fermentable fiber,&#; Dr. Cresci advises. &#;Feed your body so that it makes butyrate for you.&#;
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You may have low butyrate levels and a higher risk of infection or inflammation in your gut if:
Early research shows that butyrate can benefit your gut health, but we need more investigation to understand how it works in people and whether it has other benefits. Butyrate could encourage weight loss, stabilize blood sugars, maintain or improve intestinal function, and protect against or help treat disease.
Here are some benefits butyrate is thought to do for your body.
Studies have shown that butyrate supplements may reduce the severity of disease-causing (pathogenic) bacterial infection by lessening inflammation. This could help prevent potentially fatal conditions such as sepsis.
Researchers have also linked low levels of butyrate to an increased risk of inflammatory intestinal disease and colorectal (colon) cancer.
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Butyrate supports the gut barrier, which keeps bacteria and other microbes from entering your blood. A sodium butyrate supplement may help with irritable bowel syndrome (IBS), diverticulitis and Crohn&#;s disease.
In one study, 66 adults with irritable bowel syndrome (IBS) who took a daily dose of sodium butyrate reported less abdominal pain. In another study, 9 of 13 people with Crohn&#;s disease reported improved symptoms after taking butyric acid every day for eight weeks.
Other research shows that a diet high in dietary fiber, which encourages butyrate production, could help lower your risk of colon cancer.
One laboratory study in human cancer cell lines found that sodium butyrate stopped the growth of colorectal cancer cells and caused cancer cell death (known as apoptosis). It&#;s also been shown to reduce damage caused by cancer or chemotherapy.
People with Type 2 diabetes often experience insulin resistance and obesity. Because butyrate helps produce gut hormones that regulate blood sugar levels, it may improve these symptoms. One study showed a potential link between butyrate production and lower insulin resistance.
Butyrate-friendly foods and supplements may improve brain health. Researchers have shown that butyrate can protect your brain and improve its ability to adapt (known as plasticity).
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Early studies suggest it may help prevent or treat stroke, depression and other diseases that affect the brain, like Parkinson&#;s disease and Alzheimer&#;s disease.
Some studies suggest that butyrate may help protect your body against widespread cardiovascular diseases. Heart and blood vessel problems can increase your risk of:
The promise of butyrate extends all the way to your bedroom. Emerging evidence suggests that your gut bacteria are a source of signals that promote sleep.
A study showed that mice and rats who received butyrate showed a dramatic increase in non-rapid-eye movement (NREM) sleep for four hours after treatment. NREM includes important stages of sleep for your physical and mental health.
It&#;s not yet clear exactly how much butyrate you need. According to the United States Department of Agricultures (USDA), the recommended intake for dietary fiber is 25 grams per day for women and 35 grams per day for men, or about 28 grams as part of a 2,000-calorie daily diet. Your value may be higher or lower, depending on your calorie intake. This fiber should be a mixture of soluble (butyrate-generating) and insoluble sources.
We need more research to know if butyrate is safe and at what levels, but here are a few concerns worth noting:
In other words, more butyrate isn&#;t necessarily better. As always, when it comes to supplements, don&#;t take advice from TikTok celebs. Talk to your healthcare provider instead.
Congratulations! You&#;ve taken the first step toward gut-brain axis support, improved immune system function, and the healthiest BM&#;s of your life.
Gut+ is the do-it-all gut health supplement that combines prebiotics and postbiotics to support your natural microbiome, regulate motility, and reduce uncomfortable gut symptoms like gas and bloating.*
But how do you get started taking our newest gut health champion? Here, we&#;ll cover all of your frequently asked questions regarding Gut+, digestive health, and how this new and advanced supplement interacts with Butyrate.
Table of Contents:
So I Just Received Gut+ &#; Now What?
First, take a deep breath. Your gut symptoms aren&#;t forever &#; and Gut+ is bringing you one step closer to achieving your health goals.
Take one Gut+ capsule daily with food. Preferably, at breakfast time. This gives your supplement all day to work its magic, saving night hours for (digestive) rest and relaxation.
If you&#;re already taking a butyrate supplement, you may want to experiment with timing. Gut+ could be your morning supplement and butyrate may fit better into your lunch or dinner schedule.
Gut+ and butyrate can be taken together, too. However, if you are taking both supplements, we recommend you start slowly by taking them at separate meal times. This gives your body time to adjust to the new protocol without overwhelm.
I&#;m Sensitive to Supplements. Should I Expect Any Side Effects?
We get it. Your gut is already out of whack and you don&#;t want to make symptoms worse. The good news is, any die-off effects caused by Gut+ are short-lived. And, most people don&#;t experience side effects at all. If you&#;re worried, here are some survival tips to help curb any side effects:
Make sure you take
Gut+
with a full meal.
Want more information on butyric acid benefits? Feel free to contact us.
You can take both Gut+
and
butyrate daily. But, if you&#;re sensitive, it&#;s best to work your way up to taking both at once.
If you find that Gut+ is too much for your body to handle right now, try taking butyrate first. Butyrate has a lower dosage per capsule and doesn&#;t include Preforpro prebiotics. Once you feel comfortable, you can switch over to Gut+.
If your heart is set on Gut+, simply lower the dosage and take it once every two days until your body gets used to it.
Are you experiencing side effects? We&#;ve found that any side effects (usually mild constipation) resolve themselves after a few days.
Can I Open Gut+ Capsules and Take Them With Food or Water?
Gut+ is carefully formulated for optimal absorption and bioavailability in a one capsule dose. For this reason, we don&#;t recommend altering the capsules in any way or opening them.
Can I Have a &#;Die Off&#; Reaction with Gut+?
Yep, it&#;s totally possible to have a detox or &#;die off&#; reaction when taking Gut+, as it is with any supplement, especially for those who are sensitive. However, it&#;s unlikely. Flu-like symptoms, headache, or fatigue are typically a sign that you are killing off a pathogen and/or rebalancing the microbiome. When this happens, you may need to support your drainage pathways.
Here are some ways you can support your body through the detox process:
Liposomal glutathione
NAC
Milk thistle
Dry brushing
Infrared sauna use
Exercise/movement
Rebounding (trampoline jumping is great for your lymphatic system!)
Castor oil packs
Liquid minerals
for energy
Lymphatic massage
Support your brain and cell membranes with
BodyBio PC
People with a complicated medical history (chemical sensitivity, mold exposure, parasites, Lyme disease, SIBO, glyphosate toxicity, etc.) are generally more likely to experience a Herxheimer reaction when taking Gut+, but it isn&#;t guaranteed.
If you feel anxious about beginning Gut+, take a moment to evaluate your drainage pathways. Do you struggle to sweat? Do you poop daily? Do you digest fats correctly? It may be helpful to make some progress on these blockage issues before beginning Gut+. However, Gut+ may also be the catalyst to improving some of these issues by rebalancing your microbiome. This is an individual process, so evaluate your situation and proceed accordingly.
What are PreforPro Prebiotics?
We believe Preforpro prebiotics are the most scientifically advanced way to gently curb dysbiosis and rebalance your gut. But what are they exactly? Preforpro is a bacteriophage that gently eliminates unwanted bacteria from the gut &#; leaving room for healthy bacteria to grow and flourish. The bacteriophage prebiotics are designed to support your healthy gut bacteria without causing the bloating and gas that fiber-based prebiotics sometimes do.
Is Gut+ Meant to Replace Butyrate?
Since Gut+ contains highly absorbable tributyrin, it can be used as a replacement for your everyday butyrate supplement. Think of it as our new state-of-the-art butyrate option. However, Gut+ doesn&#;t have to replace butyrate if butyrate is working perfectly fine for you now. Some people also find added benefits in taking both supplements daily.
Do I Take Gut+ with Butyrate?
We recommend you evaluate your gut health status before replacing butyrate with Gut+. If you have a number of digestive complaints, it may be beneficial to take both supplements daily. If symptoms are mild or you are looking to maintain healthy gut status, you can probably get away with Gut+ alone. One way to evaluate your gut health is to take a test like the Thorne Onegevity Gut Test.
Should I Switch to Gut+ If I Currently Take Butyrate?
If you only have the budget or capacity for one gut supplement, it may be beneficial to switch to Gut+. This is because Gut+ includes Preforpro prebiotics and postbiotics and is unlike any other gut supplement on the market. Essentially, it&#;s a broader approach to digestive health than taking butyrate alone.
Everyone reacts differently to supplements, so we recommend you try Gut+ and butyrate for up to 1-3 months each to evaluate the benefits. Then, choose the one that works best for you.
Do I Need to Take a Probiotic Supplement with Gut+?
Broad-spectrum probiotics aren&#;t as effective as clever marketing wants you to believe. In fact, 66% of BodyBio customers said their probiotic supplement had little to no effect on their overall gut health. Yikes!
Instead of probiotics, Gut+ uses prebiotics and postbiotics to improve gut health. These provide fuel and support for the healthy bacteria that are already growing in your gut &#; allowing it to prosper naturally.
No, you don&#;t necessarily need to take a probiotic supplement in addition to Gut+. If you have a probiotic you really love, by all means, keep taking it. But if your probiotic supplement doesn&#;t provide any results, it&#;s time to ditch it and watch Gut+ do its magic.
Can Gut+ Replace My Current Probiotic Supplement?
Your microbiome is as unique as your fingerprint. It&#;s made up of trillions of microscopic bacteria that can impact your digestion for good or bad. When you take a broad-spectrum probiotic, your body doesn&#;t necessarily have the fuel (prebiotics and postbiotics) to support it. And, you&#;re shooting in the dark because you don&#;t actually know what bacterial strains your body needs.
We created Gut+ as a probiotic replacement. Its goal is to work alongside your unique microbiome &#; instead of trying to replace it with unknown probiotics. Prebiotics and postbiotics provide fuel for your natural microbiome to thrive.
Gut+ vs. Butyrate Major Differences
How about a side-by-side comparison of Gut+ versus butyrate? We&#;ve got you. Here, you can evaluate the differences between these two cutting-edge supplements and decide which one is best for you.
Major Gut+ Benefits vs. Butyrate Benefits
In addition to the benefits listed in our chart above, there are a few other things you should know about Gut+ and butyrate for gut health:
Gut+ is designed as an all-in-one gut health supplement. You no longer have to sort through dozens of pills each morning hoping that one of them will take care of your gut dysbiosis. Preforpro bacteriophage prebiotics and ultra absorbable tributyrin combine for full body benefits like blood sugar regulation, detox, digestion, and brain support. Think of it as a more advanced form of our trusted butyrate supplement.
Read more: What is Gut+?
BodyBio Butyrate has been recommended by practitioners for decades. It contains just butyrate and minerals (sodium or calcium and magnesium) for a simple approach to healing gut permeability. It focuses on gut lining integrity, supports a healthy inflammatory response, and supports blood sugar balance.
Read more: What is Butyrate?
Sodium vs. Calcium/Magnesium Butyrate
Curious to know more about the benefits of butyrate? We offer two kinds of butyrate supplements: calcium and magnesium butyrate and sodium butyrate. One of our most common questions is: which kind is best for me? Check out this blog post for answers.
We Want to Heal Digestive Distress Worldwide
Gut dysbiosis is no joke &#; and it&#;s on the rise. Around 60 to 70 million people suffer from digestive diseases worldwide. One recent US-based
study
suggests that almost 2 out of 3 people suffer from gut problems.
Our supplements have been trusted by practitioners for decades &#; and best of all, they&#;ve helped hundreds of people remember what life was like before gut symptoms. If you&#;ve tried everything to heal your gut, without any results, then we created Gut+ for you.
I&#;m Ready to Take Charge of My Gut Health
References
Almario, C. V., Ballal, M. L., Chey, W. D., Nordstrom, C., Khanna, D., & Spiegel, B. M. R. (). Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans. The American journal of gastroenterology, 113(11), &#;. https://doi.org/10./s-018--8
Liu, H., Wang, J., He, T., Becker, S., Zhang, G., Li, D., & Ma, X. (). Butyrate: A Double-Edged Sword for Health?. Advances in nutrition (Bethesda, Md.), 9(1), 21&#;29. https://doi.org/10./advances/nmx009
Żółkiewicz, J., Marzec, A., Ruszczyński, M., & Feleszko, W. (). Postbiotics-A Step Beyond Pre- and Probiotics. Nutrients, 12(8), . https://doi.org/10./nu
Slavin J. (). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), &#;. https://doi.org/10./nu
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