When should I take Rhodiola rosea extract?

01 Jul.,2024

 

How Long Does Rhodiola Rosea Take to Work? - Healthline

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Rhodiola rosea, an adaptogenic herb for well-being, could bring short-term stress and fatigue relief in about a week with consistent use.

Rhodiola rosea, also known as golden root or Arctic root, is an herb with a long history in traditional medicine due to its widely recognized health benefits. It&#;s often referred to as an adaptogen, which means it may help your body cope with stress and support overall well-being.

While the effects of the herb can vary from person to person, you may notice short-term improvements in stress and fatigue within a week or two of consistent use.

What does Rhodiola rosea do?

Rhodiola rosea L. offers a range of benefits based on traditional use and clinical research.

R. rosea may do the following:

  • Stimulate the nervous system: R. rosea has been used to support and invigorate the nervous system, potentially aiding in overall mental alertness and responsiveness.
  • Treat stress-induced fatigue and depression: The herb has been used to alleviate fatigue and feelings of depression that can result from stress and demanding lifestyles.
  • Enhance cognitive functions: Experts have studied R. rosea for its potential to improve cognitive functions and mental performance, particularly in the context of stress-related challenges.
  • Improve physical performance: Athletes and individuals have explored the herb&#;s potential to enhance physical endurance and performance, contributing to better overall fitness.
  • Manage stress-related symptoms: Rhodiola may help mitigate symptoms associated with life stress, fatigue, and burnout, promoting a sense of well-being.
  • Support cardiovascular health: Some evidence suggests that Rhodiola could positively impact cardiovascular health, addressing stress-related damage and promoting a healthier heart.
  • Benefit reproductive health: Rhodiola has shown promise in supporting reproductive health, potentially aiding in stress-induced disruptions in physiological functions.
  • Address gastrointestinal ailments: Traditional use includes treating gastrointestinal ailments, showcasing its potential benefits for digestive health.
  • Assist with impotence: Historically, healthcare professionals have used R. rosea to address impotence, suggesting a potential role in supporting male reproductive health.
  • Help manage diabetes: Animal research suggests Rhodiola rosea may be an effective supplement for diabetes management in humans.
  • Provide anticancer properties: Animal research from suggests that Rhodiola may help prevent cancer. However, more research is needed to verify this in humans.

How long does Rhodiola rosea take to work?

The effects of R. rosea may vary from person to person. Some individuals may notice short-term improvements in stress and fatigue within a week or two of regular use.

In an 8-week study, 100 participants with prolonged fatigue received a dry extract of Rhodiola rosea. They took 400 milligrams (mg) daily for 8 weeks.

The most significant improvement in fatigue was seen after just 1 week, with continuous reduction over the study period. This suggests that R. rosea might start working within the first week of use for fatigue relief.

For lasting results, consistent use over weeks to months is recommended.

How does Rhodiola rosea make you feel?

R. rosea is recognized as an &#;adaptogen.&#; This term refers to substances that enhance an organism&#;s resistance to stressors without disrupting standard biological functions, essentially exerting a &#;normalizing&#; influence.

Some potential ways Rhodiola rosea might make you feel can include:

  • reduced stress
  • improved mood
  • enhanced energy
  • better cognitive function
  • reduced fatigue
  • increased endurance
  • better sleep quality

Rhodiola rosea dosage recommendations

Typical doses of Rhodiola rosea extract range from 200&#;600 mg per day. However, dosage recommendations may vary based on the specific product, formulation, and your individual needs.

For general stress relief and mood enhancement, a lower dose might be enough. For performance enhancement in exercise, a higher dose may be considered (as high as 1,500 mg/day).

Healthcare professionals often recommend starting with a lower dose and gradually increasing it so you can observe your individual response and tolerance.

What time of day should you take Rhodiola rosea?

Rhodiola rosea can be taken in the morning for potential energy and mood benefits, or before workouts to enhance exercise performance.

Some research suggests that R. rosea extracts may have sedative and hypnotic effects possibly linked to serotonin and GABA. However, since the herb can also have stimulating effects, it&#;s probably best to avoid it just before bedtime or at least test its effects earlier in the day.

Potential side effects of Rhodiola rosea

Rhodiola rosea is generally considered safe for most people when used in recommended doses.

However, like any supplement, it can potentially cause side effects in some individuals. Here are some potential side effects and considerations associated with Rhodiola rosea:

  • overstimulation or restlessness
  • digestive upset
  • allergic reactions (rare)
  • interactions with certain medications (anticoagulants, antidiabetic drugs, and antidepressants)
  • blood pressure changes
  • manic episodes in bipolar disorder (isolated reports)

Is Rhodiola rosea safe to take long term?

Rhodiola rosea is generally considered safe when taken within recommended dosages for short to moderate periods. Multiple studies have indicated that R. rosea is generally safe for use over a period of up to 12 weeks.

However, it&#;s important to know that like all vitamins, minerals, and herbs, Rhodiola rosea is not FDA approved. This means some Rhodiola rosea supplements may not be manufactured as safely as others.

If you&#;re pregnant, breastfeeding, or have an autoimmune disease, it&#;s recommended that you avoid the herb.

Bottom line

Throughout history, Rhodiola rosea has been used to help reduce stress, enhance mood, and improve overall well-being.

Some individuals might notice changes within a week, particularly in terms of improved energy, mood, and stress reduction.

For more specific effects, like exercise performance or sleep support, several weeks of consistent use might be needed. As with any supplement, patience and personalized considerations are key when exploring its benefits.

RHODIOLA - Uses, Side Effects, and More

Abidov, M., Crendal, F., Grachev, S., Seifulla, R., and Ziegenfuss, T. Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles. Bull Exp.Biol.Med ;136(6):585-587. View abstract.

Baranov VB. Experimental trials of herbal adaptogen effect on the quality of operation activity, mental and professional work capacity. Contract 93-11-615 Stage 2 Phase I. Moscow, Russia: Russian Federation Ministry of Health Institute of Medical and Biological Problems ;

Bawa, A. S. and Khanum, F. Anti-inflammatory activity of Rhodiola rosea--"a second-generation adaptogen". Phytother.Res ;23(8):-. View abstract.

Blomkvist, J., Taube, A., and Larhammar, D. Perspective on Roseroot (Rhodiola rosea) studies. Planta Med ;75(11):-. View abstract.

Brichenko VS, Kupriyanova IE Skorokhova TF. The use of herbal adaptogens with tricyclic antidepressants in patients with psychogenic depression. Modern Problems of Pharmacology and Search for New Medicines.Tomsk, Russia: Tomsk State University Press ;58-60.

Calcabrini, C., De, Bellis R., Mancini, U., Cucchiarini, L., Potenza, L., De, Sanctis R., Patrone, V., Scesa, C., and Dacha, M. Rhodiola rosea ability to enrich cellular antioxidant defences of cultured human keratinocytes. Arch Dermatol Res ;302(3):191-200. View abstract.

Challem, J. Medical journal watch:context and applications. Rhodiola may help treat anxiety. Alternative & Complementary Therapies ;14(4):220-221.

Chen, Q. G., Zeng, Y. S., Qu, Z. Q., Tang, J. Y., Qin, Y. J., Chung, P., Wong, R., and Hagg, U. The effects of Rhodiola rosea extract on 5-HT level, cell proliferation and quantity of neurons at cerebral hippocampus of depressive rats. Phytomedicine. ;16(9):830-838. View abstract.

Chen, T. S., Liou, S. Y., and Chang, Y. L. Antioxidant evaluation of three adaptogen extracts. Am J Chin Med ;36(6):-. View abstract.

Chen, Z. G., Lu, Y., Wang, Z. T., Tao, X. Y., and Wei, D. Z. Protective effects of salidroside on hypoxia/reoxygenation injury by sodium hydrosulfite in PC12 cells. Pharmaceutical Biology (Netherlands) ;45:604-612.

De Sanctis, R., De Bellis, R., Scesa, C., Mancini, U., Cucchiarini, L., and Dacha, M. In vitro protective effect of Rhodiola rosea extract against hypochlorous acid-induced oxidative damage in human erythrocytes. Biofactors ;20(3):147-159. View abstract.

Dement'eva, L. A. and Iaremenko, K. V. [Effect of a Rhodiola extract on the tumor process in an experiment]. Vopr.Onkol ;33(7):57-60. View abstract.

Duhan, O. M., Baryliak, I. R., Nester, T. I., Dvornyk, A. S., and Kunakh, V. A. [The antimutagenic activity of biomass extracts from the cultured cells of medicinal plants in the Ames test]. Tsitol.Genet. ;33(6):19-25. View abstract.

Earnest, C. P., Morss, G. M., Wyatt, F., Jordan, A. N., Colson, S., Church, T. S., Fitzgerald, Y., Autrey, L., Jurca, R., and Lucia, A. Effects of a commercial herbal-based formula on exercise performance in cyclists. Med Sci Sports Exerc. ;36(3):504-509. View abstract.

Evdokimov, V. G. [Effect of cryopowder Rhodiola rosae L. on cardiorespiratory parameters and physical performance of humans]. Aviakosm.Ekolog.Med ;43(6):52-56. View abstract.

Evstatieva, L., Todorova, M., Antonova, D., and Staneva, J. Chemical composition of the essential oils of Rhodiola rosea L. of three different origins. Pharmacogn.Mag. ;6(24):256-258. View abstract.

Fintelmann, V. and Gruenwald, J. Efficacy and tolerability of a Rhodiola rosea extract in adults with physical and cognitive deficiencies. Adv.Ther ;24(4):929-939. View abstract.

Gupta, V., Lahiri, S. S., Sultana, S., Tulsawani, R. K., and Kumar, R. Anti-oxidative effect of Rhodiola imbricata root extract in rats during cold, hypoxia and restraint (C-H-R) exposure and post-stress recovery. Food Chem.Toxicol. ;48(4):-. View abstract.

Hu, X., Lin, S., Yu, D., Qiu, S., Zhang, X., and Mei, R. A preliminary study: the anti-proliferation effect of salidroside on different human cancer cell lines. Cell Biol Toxicol. ;26(6):499-507. View abstract.

Hu, X., Zhang, X., Qiu, S., Yu, D., and Lin, S. Salidroside induces cell-cycle arrest and apoptosis in human breast cancer cells. Biochem.Biophys.Res Commun. 7-16-;398(1):62-67. View abstract.

Huang, S. C., Lee, F. T., Kuo, T. Y., Yang, J. H., and Chien, C. T. Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat. Chin J Physiol 10-31-;52(5):316-324. View abstract.

Hung, S. K., Perry, R., and Ernst, E. The effectiveness and efficacy of Rhodiola rosea L.: A systematic review of randomized clinical trials. Phytomedicine. 2-15-;18(4):235-244. View abstract.

Iovieno, N., Dalton, E. D., Fava, M., and Mischoulon, D. Second-tier natural antidepressants: review and critique. J Affect.Disord. ;130(3):343-357. View abstract.

Ip, S. P., Che, C. T., and Leung, P. S. Association of free radicals and the tissue renin-angiotensin system: prospective effects of Rhodiola, a genus of Chinese herb, on hypoxia-induced pancreatic injury. JOP. ;2(1):16-25. View abstract.

Jafari, M., Felgner, J. S., Bussel, I. I., Hutchili, T., Khodayari, B., Rose, M. R., Vince-Cruz, C., and Mueller, L. D. Rhodiola: a promising anti-aging Chinese herb. Rejuvenation.Res ;10(4):587-602. View abstract.

Jeong, H. J., Ryu, Y. B., Park, S. J., Kim, J. H., Kwon, H. J., Kim, J. H., Park, K. H., Rho, M. C., and Lee, W. S. Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. Bioorg.Med Chem. 10-1-;17(19):-. View abstract.

Kiefer, D. Rhodiola rosea for General Anxiety Disorder. Alternative Medicine Alert ;11(6):61-65.

Kobayashi, K., Yamada, K., Murata, T., Hasegawa, T., Takano, F., Koga, K., Fushiya, S., Batkhuu, J., and Yoshizaki, F. Constituents of Rhodiola rosea showing inhibitory effect on lipase activity in mouse plasma and alimentary canal. Planta Med ;74(14):-. View abstract.

Krasik ED, Morozova ES Petrova KP Ragulina GA Shemetova LA Shuvaev VP. Therapy of asthenic conditions: clinical perspectives of application of Rhodiola rosea extract (golden root). Proceedings Modern problems in psycho-pharmacology.Kemerovo-city, Russia: Siberian Branch of Russian Academy of Sciences ;298-330.

Lazarova, M. B., Petkov, V. D., Markovska, V. L., Petkov, V. V., and Mosharrof, A. Effects of meclofenoxate and Extr. Rhodiolae roseae L. on electroconvulsive shock-impaired learning and memory in rats. Methods Find.Exp.Clin.Pharmacol. ;8(9):547-552. View abstract.

Lee, F. T., Kuo, T. Y., Liou, S. Y., and Chien, C. T. Chronic Rhodiola rosea extract supplementation enforces exhaustive swimming tolerance. Am J Chin Med ;37(3):557-572. View abstract.

Li, H. B., Ge, Y. K., Zheng, X. X., and Zhang, L. Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase. Eur J Pharmacol 7-7-;588(2-3):165-169. View abstract.

Li, X., Ye, X., Li, X., Sun, X., Liang, Q., Tao, L., Kang, X., and Chen, J. Salidroside protects against MPP(+)-induced apoptosis in PC12 cells by inhibiting the NO pathway. Brain Res 1-15-; View abstract.

Mao, G. X., Wang, Y., Qiu, Q., Deng, H. B., Yuan, L. G., Li, R. G., Song, D. Q., Li, Y. Y., Li, D. D., and Wang, Z. Salidroside protects human fibroblast cells from premature senescence induced by H(2)O(2) partly through modulating oxidative status. Mech.Ageing Dev ;131(11-12):723-731. View abstract.

Mao, Y., Zhang, X., Zhang, X., and Lu, G. Development of an HPLC method for the determination of salidroside in beagle dog plasma after administration of salidroside injection: application to a pharmacokinetics study. J Sep.Sci ;30(18):-. View abstract.

Maslov, L. N., Lishmanov, Y. B., Arbuzov, A. G., Krylatov, A. V., Budankova, E. V., Konkovskaya, Y. N., Burkova, V. N., and Severova, E. A. Antiarrhythmic activity of phytoadaptogens in short-term ischemia-reperfusion of the heart and postinfarction cardiosclerosis. Bull Exp.Biol Med ;147(3):331-334. View abstract.

Narimanian, M., Badalyan, M., Panosyan, V., Gabrielyan, E., Panossian, A., Wikman, G., and Wagner, H. Impact of Chisan (ADAPT-232) on the quality-of-life and its efficacy as an adjuvant in the treatment of acute non-specific pneumonia. Phytomedicine ;12(10):723-729. View abstract.

Noreen, E., Buckley, J., and Lewis, S. The effects of an acute dose of Rhodiola rosea on exercise performance and cognitive function. Journal of the International Society of Sports Nutrition ;6(Suppl 1):14p.

Panossian, A., Hovhannisyan, A., Abrahamyan, H., Gabrielyan, E., and Wikman, G. Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats. Phytother.Res ;23(3):351-357. View abstract.

Panossian, A., Nikoyan, N., Ohanyan, N., Hovhannisyan, A., Abrahamyan, H., Gabrielyan, E., and Wikman, G. Comparative study of Rhodiola preparations on behavioral despair of rats. Phytomedicine. ;15(1-2):84-91. View abstract.

Panossian, A., Wikman, G., and Sarris, J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine. ;17(7):481-493. View abstract.

Provino, R. The role of adaptogens in stress management. Australian Journal of Medical Herbalism ;22(2):41-49.

Qian, E. W., Ge, D. T., and Kong, S. K. Salidroside promotes erythropoiesis and protects erythroblasts against oxidative stress by up-regulating glutathione peroxidase and thioredoxin. J Ethnopharmacol. 1-27-;133(2):308-314. View abstract.

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Qu, Z. Q., Zhou, Y., Zeng, Y. S., Li, Y., and Chung, P. Pretreatment with Rhodiola rosea extract reduces cognitive impairment induced by intracerebroventricular streptozotocin in rats: implication of anti-oxidative and neuroprotective effects. Biomed.Environ Sci ;22(4):318-326. View abstract.

Rohloff, J. Volatiles from rhizomes of Rhodiola rosea L. Phytochemistry ;59(6):655-661. View abstract.

Schriner, S. E., Abrahamyan, A., Avanessian, A., Bussel, I., Maler, S., Gazarian, M., Holmbeck, M. A., and Jafari, M. Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea. Free Radic.Res ;43(9):836-843. View abstract.

Schriner, S. E., Avanesian, A., Liu, Y., Luesch, H., and Jafari, M. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses. Free Radic.Biol Med 9-1-;47(5):577-584. View abstract.

Schulzz, V. Rhodiola rosea radix extract for the treatment of mild to moderate depression? Results of a placebo-controlled clinical study. KIM - Komplementare und Integrative Medizin, Artztezeitschrift fur Naturheilverfahren ;3(2):36-41.

Skarpanska-Stejnborn, A., Pilaczynska-Szczesniak, L., Basta, P., and Deskur-Smielecka, E. The influence of supplementation with Rhodiola rosea L. extract on selected redox parameters in professional rowers. Int J Sport Nutr Exerc.Metab ;19(2):186-199. View abstract.

Ssaratikov, A. S., Krasnov, E. A., Chnikina, L. A., Duvidson, L. M., Sotova, M. I., Marina, T. F., Nechoda, M. F., Axenova, R. A., and Tscherdinzeff, S. G. [Rhodiolosid, a new glycoside from Rhodiola rosea and its pharmacological properties]. Pharmazie ;23(7):392-395. View abstract.

Tan, C. B., Gao, M., Xu, W. R., Yang, X. Y., Zhu, X. M., and Du, G. H. Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride. Biol Pharm Bull ;32(8):-. View abstract.

Udintsev, S. N. and Schakhov, V. P. Decrease of cyclophosphamide haematotoxicity by Rhodiola rosea root extract in mice with Ehrlich and Lewis transplantable tumors. Eur.J Cancer ;27(9):. View abstract.

Udintsev, S. N. and Shakhov, V. P. The role of humoral factors of regenerating liver in the development of experimental tumors and the effect of Rhodiola rosea extract on this process. Neoplasma ;38(3):323-331. View abstract.

van, Diermen D., Marston, A., Bravo, J., Reist, M., Carrupt, P. A., and Hostettmann, K. Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. 3-18-;122(2):397-401. View abstract.

Walker, T., Altobelli, S., Caprihan, A., and Robergs, R. Muscle phosphate kinetics following Rhodiola Rosea ingestion. Journal of Exercise Physiology Online ;9(2):11.

Wang, H., Ding, Y., Zhou, J., Sun, X., and Wang, S. The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3. Phytomedicine. ;16(2-3):146-155. View abstract.

Wiegant, F. A., Surinova, S., Ytsma, E., Langelaar-Makkinje, M., Wikman, G., and Post, J. A. Plant adaptogens increase lifespan and stress resistance in C. elegans. Biogerontology. ;10(1):27-42. View abstract.

Wu, T., Zhou, H., Jin, Z., Bi, S., Yang, X., Yi, D., and Liu, W. Cardioprotection of salidroside from ischemia/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins. Eur J Pharmacol 6-24-;613(1-3):93-99. View abstract.

Wu, Y. L., Piao, D. M., Han, X. H., and Nan, J. X. Protective effects of salidroside against acetaminophen-induced toxicity in mice. Biol Pharm Bull ;31(8):-. View abstract.

Xu, K. J., Zhang, S. F., and Li, Q. X. [Preventive and treatment effect of composite Rhodiolae on acute lung injury in patients with severe pulmonary hypertension during extracorporeal circulation]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. ;23(9):648-650. View abstract.

Yu, S., Liu, L., Wen, T., Liu, Y., Wang, D., He, Y., Liang, Y., Liu, X., Xie, L., Wang, G., and Wei, W. Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of salidroside in rat plasma: application to the pharmacokinetics study. J Chromatogr.B Analyt.Technol.Biomed.Life Sci 1-1-;861(1):10-15. View abstract.

Zaiteva, S. I., Matveeva, S. L., Gerasimova, T. G., Pashkov, Y. N., Butov, D. A., Pylypchuck, V. S., Frolov, V. M., and Kutsyna, G. A. Efficacy and safety of phytoconcentrate Dzherelo (Immunoxel) in treatment of patients with multi-drug resistant TB (MDR-TB) in comparison to standartd chemotherapy. Research Journal of Medical Sciences ;3(2):36-41.

Zhang, L., Yu, H., Zhao, X., Lin, X., Tan, C., Cao, G., and Wang, Z. Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells. Neurochem.Int ;57(5):547-555. View abstract.

Zhang, Z. H., Feng, S. H., Hu, G. D., Cao, Z. K., and Wang, L. Y. [Effect of Rhodiola kirilowii (Regel.) Maxim on preventing high altitude reactions. A comparison of cardiopulmonary function in villagers at various altitudes]. Zhongguo Zhong.Yao Za Zhi. ;14(11):687-90, 704. View abstract.

Zheng, K. Y., Guo, A. J., Bi, C. W., Zhu, K. Y., Chan, G. K., Fu, Q., Xu, S. L., Zhan, J. Y., Lau, D. T., Dong, T. T., Choi, R. C., and Tsim, K. W. The Extract of Rhodiolae Crenulatae Radix et Rhizoma Induces the Accumulation of HIF-1alpha via Blocking the Degradation Pathway in Cultured Kidney Fibroblasts. Planta Med 12-14-; View abstract.

Zhong, H., Xin, H., Wu, L. X., and Zhu, Y. Z. Salidroside attenuates apoptosis in ischemic cardiomyocytes: a mechanism through a mitochondria-dependent pathway. J Pharmacol Sci ;114(4):399-408. View abstract.

Zotova MI. The effect of Rhodiola rosea extract on mental working activity in man. In Collection of Reports at 3rd Scientific Conference of Physiologists, Biochemists and Pharmacologists of Western Siberia, Tomsk ;298-299.

Abidov M, Grachev S, Seifulla RD, Ziegenfuss TN. Extract of Rhodiola rosea radix reduces the level of C-reactive protein and creatinine kinase in the blood. Bull Exp Biol Med ;138:63-4. View abstract.

Akgul Y, Ferreira D, Abourashed EA, Khan IA. Lotaustralin from Rhodiola rosea roots. Fitoterapia ;75:612-4. View abstract.

Apostolidis E, Kwon YI, Shetty K. Potential of cranberry-based herbal synergies for diabetes and hypertension management. Asia Pac J Clin Nutr ;15:433-41. View abstract.

Aslanyan G, Amroyan E, Gabrielyan E, et al. Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions. Phytomedicine ;17:494-9. View abstract.

Azizov, A. P. and Seifulla, R. D. [The effect of elton, leveton, fitoton and adapton on the work capacity of experimental animals]. Eksp Klin Farmakol ;61(3):61-63. View abstract.

Ballmann CG, Maze SB, Wells AC, Marshall MM, Rogers RR. Effects of short-term Rhodiola rosea (Golden Root Extract) supplementation on anaerobic exercise performance. J Sports Sci. ;37(9):998-. View abstract.

Bocharova OA, Matveev BP, Baryshnikov AI, et al. [The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer]. Urol Nefrol (Mosk) ;:46-7. View abstract.

Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med ;14:175-80. View abstract.

Cai T, Verze P, Messenio P, et al. Rhodiola rosea, folic acid, zinc, and biotin (EndEP) is able to improve ejaculatory control in patients affected by lifelong premature ejaculation: results from a phase I-II study. Exp Ther Med. Oct;12(4):-87. View abstract.

Colson SN, Wyatt FB, Johnston DL, et al. Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation. J Strength Cond Res ;19:358-63. View abstract.

Cropley M, Banks AP, Boyle J. The effects of Rhodiola rosea L. Extract on anxiety, stress, cognition, and other mood symptoms. Phytother Res. Dec;29(12):-9. View abstract.

Darbinyan G, Aslanyan G, Amroyan E. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry ;61:343-8. View abstract.

Darbinyan V, Kteyan A, Panossian A, et al. Rhodiola rosea in stress induced fatigue - a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine ;7:365-71. View abstract.

De Bock K, Eijnde BO, Ramaekers M, Hespel P. Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab ;14:298-307. View abstract.

Edwards D, Heufelder A, Zimmermann A. Therapeutic effects and safety of Rhodiola rosea extract WS® in subjects with life-stress symptoms--results of an open-label study. Phytother Res ;26(8):-5. View abstract.

Gao L, Wu C, Liao Y, Wang J. Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial. J Affect Disord. ;265:99-103. View abstract.

Ha Z, Zhu Y, Zhang X, et al. The effect of rhodiola and acetazolamide on the sleep architecture and blood oxygen saturation in men living at high altitude. Zhonghua Jie He He Hu Xi Za Zhi ;25:527-30. View abstract.

Hellum BH, Tosse A, Hoybakk K, et al. Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea. Planta Med ;76:331-8. View abstract.

Karosanidze I, Kiladze U, Kirtadze N, et al. Efficacy of adaptogens in patients with long COVID-19: a randomized, quadruple-blind, placebo-controlled trial. Pharmaceuticals (Basel) ;15(3):345. View abstract.

Kasper S, Deniel A. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms. Neuropsychiatr Dis Treat. Mar 22;13:889-98. View abstract.

Kelly GS. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev ;6:293-302. View abstract.

Kim SH, Hyun SH, Choung SY. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. Biofactors ;26:209-19. View abstract.

Kormosh, N., Laktionov, K., and Antoshechkina, M. Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer. Phytother Res ;20(5):424-425. View abstract.

Kwon YI, Jang HD, Shetty K. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr ;15:425-32. View abstract.

Li HX, Sze SC, Tong Y, Ng TB. Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes. J Ethnopharmacol ;123:257-66. View abstract.

Li T, Xu L, Sun C. Pharmacological studies on the sedative and hypnotic effect of salidroside from the Chinese medicinal plant Rhodiola sachalinensis. Phytomedicine ;14:601-4. View abstract.

Lishmanov IB, Maslova LV, Maslov LN, Dan'shina EN. [The anti-arrhythmia effect of Rhodiola rosea and its possible mechanism]. Bull Eksp Biol Med ;116:175-6. View abstract.

Lishmanov IB, Naumova AV, Afanas'ev SA, Maslov LN. [Contribution of the opioid system to realization of inotropic effects of Rhodiola rosea extracts in ischemic and reperfusion heart damage in vitro]. Eksp Klin Farmakol ;60:34-6. View abstract.

Liu C, Zhao H, Yan Y, et al. Synergistic Effect of Rhodiola rosea and Caffeine Supplementation on the Improvement of Muscle Strength and Muscular Endurance: A Pilot Study for Rats, Resistance Exercise-Untrained and -Trained Volunteers. Nutrients ;15(3):582. View abstract.

Ma G, Li W, Dou D, et al. Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea. Chem Pharm Bull ;54:-33. View abstract.

Maimeskulova LA, Maslov LN, Lishmanov IB, Krasnov EA. [The participation of the mu-, delta- and kappa-opioid receptors in the realization of the anti-arrhythmia effect of Rhodiola rosea]. Eksp Klin Farmakol ;60:38-9. View abstract.

Majewska A, Hoser G, Furmanowa M, et al. Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells. J Ethnopharmacol ;103:43-52. View abstract.

Maslova LV, Kondrat'ev BI, Maslov LN, Lishmanov IB. [The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress]. Eksp Klin Farmakol ;57:61-3. View abstract.

Ming DS, Hillhouse BJ, Guns ES, et al. Bioactive compounds from Rhodiola rosea (Crassulaceae). Phytother Res ;19:740-3. View abstract.

Mishra KP, Chanda S, Shukla K, Ganju L. Adjuvant effect of aqueous extract of Rhodiola imbricate rhizome on the immune responses to tetanus toxoid and ovalbumin in rats. Immunopharmacol Immunotoxicol ;32:141-6. View abstract.

Mishra KP, Ganju L, Chanda S, et al. Aqueous extract of Rhodiola imbricate rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro. Immunobiology ;214:27-31. View abstract.

Noah L, Morel V, Bertin C, et al. Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study. Nutrients. Apr 29;14(9):. View abstract.

Noreen EE, Buckley JG, Lewis SL, Brandauer J, Stuempfle KJ. The effects of an acute dose of Rhodiola rosea on endurance exercise performance. J Strength Cond Res ;27(3):839-47. View abstract.

Olsson EM, von Scheele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardized extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress related fatigue. Planta Med ;75:105-12. View abstract.

Parisi A, Tranchita E, Duranti G, et al. Effects of chronic Rhodiola Rosea supplementation on sport performance and antioxidant capacity in trained male: preliminary results. J Sports Med Phys Fitness ;50:57-63. View abstract.

Perfumi M, Mattioli L. Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. Phytother Res ;21:37-43. View abstract.

Petkov VD, Yonkov D, Mosharoff A, et al. Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory. Acta Physiol Pharmacol Bulg ;12:3-16. View abstract.

Pkhaladze L, Davidova N, Khomasuridze A, Shengelia R, Panossian AG. Actaea racemosa L. is more effective in combination with Rhodiola rosea L. for relief of menopausal symptoms: a randomized, double-blind, placebo-controlled study. Pharmaceuticals (Basel). ;13(5):102. View abstract.

Roumanille R, Vernus B, Brioche T, et al. Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats. J Int Soc Sports Nutr ;17(1):58. View abstract.

Ryan ED, Gerstner GR, Mota JA, et al. The Acute Effects of a Multi-Ingredient Herbal Supplement on Performance Fatigability: A Double-Blind, Randomized, and Placebo-Controlled Trial. J Diet Suppl ;18(5):507-516. View abstract.

Salikhova RA, Aleksandrova IV, Mazurik VK, et al. [Effect of Rhodiola rosea on the yield of mutation alterations and DNA repair in bone marrow cells]. Patol Fiziol Eksp Ter ;:22-4. View abstract.

Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce. World J Biol Psychiatry. ;23(6):424-455. View abstract.

Schutgens FW, Neogi P, van Wijk EP, et al. The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment. Phytother Res ;23:-8. View abstract.

Shanely RA, Nieman DC, Zwetsloot KA, et al. Evaluation of Rhodiola rosea supplementation on skeletal muscle damage and inflammation in runners following a competitive marathon. Brain Behav Immun ;39:204-10. View abstract.

Shevtsov VA, Zholus BI, Shervarly VI, et al. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine ;10:95-105. View abstract.

Skopriska-Rozewska E, Wojcik R, Siwicki AK, et al. The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats. Pol J Vet Sci ;11:105-11. View abstract.

Spasov AA, Mandrikov VB, Mironova IA. The effect of a preparation rodakson on the psychophysiological and physical adaptation of students to an academic load. Eksp Klin Farmakol ;63:76-8. View abstract.

Spasov AA, Wikman GK, Mandrikov VB, et al. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine ;7:85-89. View abstract.

Thu OK, Nilsen OG, Hellum B. In vitro inhibition of cytochrome P-450 activities and quantification of constituents in a selection of commercial Rhodiola rosea products. Pharm Bio. Dec;54(12):-. View abstract.

Thu OK, Spigset O, Nilsen OG, Hellum B. Effect of commercial Rhodiola rosea on CYP enzyme activity in humans. Eur J Clin Pharmacol. Mar;72(3):295-300. View abstract.

Udintsev SN, Krylova SG, Fomina TI. [The enhancement of the efficacy of adriamycin by using hepatoprotectors of plant origin in metastases of Ehrlich's adenocarcinoma to the liver in mice]. Vopr Onkol ;38:-22. View abstract.

Udintsev SN, Shakhov VP. [Changes in clonogenic properties of bone marrow and transplantable mice tumor cells during combined use of cyclophosphane and biological response modifiers of adaptogenic origin]. Eksp Onko ;12:55-6. View abstract.

Walker TB, Altobelli SA, Caprihan A, Robergs RA. Failure of Rhodiola rosea to alter skeletal muscle phosphate kinetics in trained men. Metabolism ;56:-7. View abstract.

Wiedenfeld H, Dumaa M, Malinowski M, et al. Phytochemical and analytical studies of extracts from Rhodiola rosea and Rhodiola quadrifida. Pharmazie ;62:308-11. View abstract.

Williams TD, Langley HN, Roberson CC, Rogers RR, Ballmann CG. Effects of short-term golden root extract (Rhodiola rosea) supplementation on resistance exercise performance. Int J Environ Res Public Health ;18(13):. View abstract.

Wing SL, Askew EW, Luetkemeier MJ, et al. Lack of effect of Rhodiola or oxygenated water supplementation on hypoxemia and oxidative stress. Wilderness Environ Med ;14:9-16. View abstract.

Zhang H, Shen WS, Gao CH, Deng LC, Shen D. Protective effects of salidroside on epirubicin-induced early left ventricular regional systolic dysfunction in patients with breast cancer. Drugs R D ;12(2):101-6. View abstract.

Zhang L, Yu H, Sun Y, et al. Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells. Eur J Pharmacol. ;564:18-25. View abstract.

Zhang ZJ, Tong Y, Zou J, et al. Dietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers. Chin J Integr Med ;15:177-83. View abstract.

Zubeldia JM, Nabi HA, Jimenez del Río M, Genovese J. Exploring new applications for Rhodiola rosea: can we improve the quality of life of patients with short-term hypothyroidism induced by hormone withdrawal? J Med Food ;13:-92. View abstract.

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