This section provides an overview for isobutyric acids as well as their applications and principles. Also, please take a look at the list of 17 isobutyric acid manufacturers and their company rankings. Here are the top-ranked isobutyric acid companies as of August, : 1.Restek Corporation., 2.Chemex Chemicals, 3.HAZMAT Resource, Inc..
You will get efficient and thoughtful service from Yufeng.
Isobutyric acid is an organic compound with the chemical formula C4H8O2 and the characteristic formula (CH3)2CHCOOH.
It is one of the structural isomers of butyric acid, a volatile aliphatic carboxylic acid. Its IUPAC nomenclature is 2-methylpropanoic acid, and its CAS number is 79-31-2.
In the chemical field, isobutyric acids are used for the synthesis of isobutyric esters such as methyl isobutyrate, propyl ester, isoamyl ester, and benzyl ester, and the production of isobutyronitrile intermediate.
It is also used in the food industry as an edible flavor. Specifically, it is mainly used in the production of butter, apples, caramel, cheese, bread, and yeast. Other uses include the production of perfumes and perfume esters, pharmaceuticals, solvents for paints, disinfectants, varnishes, plasticizers, leather, and tanning agents.
Figure 1. Basic Information on Isobutyric Acids
Isobutyric acids have a molecular weight of 88.11, a melting point of -47°C, and a boiling point of 154°C. It is a colorless liquid at room temperature. it has an unpleasant rancid buttery odor similar to that of n-butyric acid.
It has a density of 0.950 g/mL and an acid dissociation constant pKa of 4.84. It is extremely soluble in organic solvents such as ethanol and ether and dissolves in 6 times as much water.
Isobutyric acids are generally sold as reagent products for research and development and as flavoring agents (food additives). In R&D reagent products, isobutyric acid is available in 25mL, 100mL, and 500mL volumes, and is usually supplied in volumes that are easy to handle in the laboratory.
They are handled as reagent products that can be stored at room temperature. For those sold as food additives or flavorings, individual inquiries to the manufacturer are required.
Figure 2. Example of Synthesis of Isobutyric Acids
Are you interested in learning more about overbased magnesium sulfonate in suspension? Contact us today to secure an expert consultation!
Isobutyric acids can be synthesized by oxidizing isobutyl alcohol with an appropriate oxidant (potassium dichromate/sulfuric acid conditions, etc.). This is done via isobutyraldehyde as an intermediate.
Other methods include the hydrocarboxylation of propylene (Koch reaction). Industrially, isobutyric acids are a byproduct of n-butanol production.
Laboratory methods include hydrolysis of isobutyl nitrile under basic conditions to obtain isobutyl alcohol, followed by oxidation, and direct treatment of methacrylic acid with sodium amalgam (Na(Hg)) to obtain isobutyric acids.
Figure 3. Examples of Derivatives of Isobutyric Acids
Isobutyric acids show the typical reactivity seen in carboxylic acids in general, yielding derivatives such as amides (-CONH2), acid anhydrides (-CO-O-CO-), and acid chlorides (-COCl). Reaction with chromic acid produces acetone. The substance obtained by oxidizing isobutyric acids with potassium permanganate under basic conditions is α-hydroxyisobutyric acid.
Isobutyric acids have various hazardous properties and are classified by the GHS classification as follows
Isobutyric acids may be altered by light. Avoid high temperatures, direct sunlight, heat, flames, sparks, static electricity, and sparks. Strong oxidizers are listed as a miscibility hazard. Hazardous decomposition products are carbon monoxide and carbon dioxide.
Isobutyric acids are regulated by law due to their hazardous properties. Under the Fire Service Act, it is classified as a hazardous material, Class IV, Petroleum No. 2, Hazardous Rank III, and under the Industrial Safety and Health Act, it is classified as a hazardous material and flammable substance. It must be handled correctly in compliance with laws and regulations.
If you are interested in learning more about product availability in your area, please complete the &#;Make an inquiry&#; form on this page.
If applicable, authorized distributors are in the regions listed below, with more details provided in the &#;Authorized distributors&#; section.